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Your doctor may occasionally change your dose. Het heeft geringe anticholinerge en antihistaminerge werking. It may take up to 2 weeks before your symptoms improve Het remt de heropname van serotonine sterker dan van noradrenaline. It may also be used for relief of an anxiety disorder (e. 1 Acute insomnia is short-term and may last for days or weeks Trazodone overdose can be fatal when mixed with alcohol, Barbiturates, or Sedatives such as Valium. Soms bij dementie en slapeloosheid, bijvoorbeeld bij de angststoornis posttraumatische stressstoornis (PTSS) of in de laatste levensfase (palliatieve zorg). Since it has sedative or hypnotic effects, meaning that it causes drowsiness, it is also helpful for treating insomnia or acute insomnia. Het sederend effect kan een gevolg zijn van de α 1 -adrenerge blokkade Trazodone is available in the form of 25 mg, 50 mg, 100 mg, 150 mg, and 300 mg tablets for oral ingestion. 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