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16 in conjunction with a same-day complaint against FDA and HHS seeking 10 years marketing exclusivity for Desyrel. Chemical formula: C19H22ClN5O Drugbank ID: DB00656 ATC code: N06AX05. 3 Screen for Bipolar Disorder Prior to Starting DESYREL Prior to initiating treatment with DESYREL or another antidepressant, screen patients for a personal or family history of bipolar disorder, mania, or hypomania [see Warnings and Precautions (5. (Indications) This medication is an antidepressant, prescribed for depression and anxiety. Brand names: Desyrel, Oleptro, Desyrel Dividose Drug class: phenylpiperazine antidepressants. This product is available in the following dosage forms: Tablet Trazodone is excreted primarily as metabolites by the kidneys and possesses a biphasic elimination half-life of 4. 5 Trazodone was approved for medical use in December 1981 in the US by the FDA as an anti-depressant medication, Desyrel. 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